Primary cutaneous amyloidosis explained

Primary cutaneous amyloidosis is a form of amyloidosis associated with oncostatin M receptor.^{[2] [3]} This type of amyloidosis has been divided into the following types:^[4]

• Macular amyloidosis is a cutaneous condition characterized by itchy, brown, rippled macules usually located on the interscapular region of the back. Combined cases of lichen and macular amyloidosis are termed biphasic amyloidosis, and provide support to the theory that these two variants of amyloidosis exist on the same disease spectrum.^[5]
• Lichen amyloidosis is a cutaneous condition characterized by the appearance of occasionally itchy lichenoid papules, typically appearing bilaterally on the shins.

• Nodular amyloidosis is a rare cutaneous condition characterized by nodules that involve the acral areas.

See also

• Amyloidosis
• List of cutaneous conditions

Notes and References

1. Web site: Primary cutaneous amyloidosis Genetic and Rare Diseases Information Center (GARD) – an NCATS Program . rarediseases.info.nih.gov . 18 April 2019.
2. Web site: Amyloid .
3. Arita K, South AP, Hans-Filho G, etal . Oncostatin M receptor-beta mutations underlie familial primary localized cutaneous amyloidosis . Am. J. Hum. Genet. . 82 . 1 . 73–80 . January 2008 . 18179886 . 10.1016/j.ajhg.2007.09.002 . 2253984.
4. Book: James, William D. . Berger, Timothy G. . Andrews' Diseases of the Skin: clinical Dermatology . Saunders Elsevier . 2006 . 978-0-7216-2921-6 . etal.
5. http://dermatology-s10.cdlib.org/125/UCDcases/amlyoid/craig.html Lichen amyloidosis of the auricular concha