Nodavirus endopeptidase explained

Nodavirus endopeptidase (Black Beetle virus endopeptidase, Flock House virus endopeptidase) is an enzyme.^{[1] [2]} This enzyme catalyses the following chemical reaction

Hydrolysis of an asparaginyl bond involved in the maturation of the structural protein of the virus, typically -Asn-Ala- or -Asn-Phe-

The enzyme is coded by several nodaviruses that are insect pathogens.

Notes and References

1. Zlotnick A, Reddy VS, Dasgupta R, Schneemann A, Ray WJ, Rueckert RR, Johnson JE . Capsid assembly in a family of animal viruses primes an autoproteolytic maturation that depends on a single aspartic acid residue . The Journal of Biological Chemistry . 269 . 18 . 13680–4 . May 1994 . 8175803 .
2. Book: Nodavirus endopeptidase . Handbook of Proteolytic Enzymes . Johnson JE, Schneemann A . 1998 . 964–967 . Barrett AJ, Rawlings ND, Woessner JF . Handbook of Proteolytic Enzymes . London .