Equine estrogen explained

Equine estrogens, or horse estrogens, are estrogens found in horses.^{[1] [2] [3]} They include the following:

• Estradiol
• Estrone
• Equilin (Δ⁷-estrone)
• Equilenin (Δ^6,8-estrone)
• 17α-Dihydroequilin (Δ⁷-17α-estradiol)
• 17β-Dihydroequilin (Δ⁷-17β-estradiol)
• 17α-Dihydroequilenin (Δ^6,8-17α-estradiol)
• 17β-Dihydroequilenin (Δ^6,8-17β-estradiol)
• 8,9-Dehydroestrone (Δ⁸-estrone)
• 8,9-Dehydroestradiol (Δ⁸-17β-estradiol)
• Hippulin (Δ⁸-14-isoestrone)

As well as their conjugates, such as estrone sulfate.

Equine estrogens are found in the human medications conjugated estrogens (Premarin) and esterified estrogens (Estratab, Menest).

See also

• List of estrogens § Equine estrogens

Notes and References

1. Kuhl H . Pharmacology of estrogens and progestogens: influence of different routes of administration . Climacteric . 8 . 3–63 . 2005 . Suppl 1 . 16112947 . 10.1080/13697130500148875 . 24616324 .
2. Bhavnani BR, Tam SP, Lu X . Structure activity relationships and differential interactions and functional activity of various equine estrogens mediated via estrogen receptors (ERs) ERalpha and ERbeta . Endocrinology . 149 . 10 . 4857–70 . October 2008 . 18599548 . 10.1210/en.2008-0304 . free .
3. Bhavnani BR . Estrogens and menopause: pharmacology of conjugated equine estrogens and their potential role in the prevention of neurodegenerative diseases such as Alzheimer's . J. Steroid Biochem. Mol. Biol. . 85 . 2–5 . 473–82 . June 2003 . 12943738 . 10.1016/s0960-0760(03)00220-6 . 45552896 .