Caffeoylquinic acid explained

Caffeoylquinic acids (CQA) are compounds composed of a quinic acid core, acylated with one or more caffeoyl groups. There is a positive correlation between the number of caffeoyl groups bound to quinic acid and the rate of ATP production.^[1] Compounds of this class include:

• Chlorogenic acid (3-O-caffeoylquinic acid or 3-CQA)
• 4-O-caffeoylquinic acid (crypto-chlorogenic acid or 4-CQA)
• 5-O-caffeoylquinic acid (neo-chlorogenic acid or 5-CQA)
• 1,5-diCQA
• 3,4-diCQA
• 3,5-diCQA
• 4,5-diCQA

Notes and References

1. Miyamae, Y. . Kurisu, M. . Han, J. . Isoda, H. . Shigemori, H. . 2011. Structure–Activity Relationship of Caffeoylquinic Acids on the Accelerating Activity on ATP Production. Chemical and Pharmaceutical Bulletin. 59 . 4. 502–507. 21467684.