Paraneoplastic acrokeratosis explained

Paraneoplastic acrokeratosis is a skin condition characterized by psoriasiform changes of fingers, toes, ears, and nose, with involvement of the nails and periungual tissues being characteristic and indistinguishable from psoriatic nails.^[1] The condition is associated with carcinomas of the upper aerodigestive tract.^[2]

History

A case was first reported by Henri Gougerot and C. Grupper in 1922.^{[3] [4]} Andre Bazex described it as a paraneoplastic syndrome in 1965.^{[3] [5]}

See also

• List of cutaneous conditions
• Nail anatomy
• List of cutaneous conditions associated with increased risk of nonmelanoma skin cancer

Notes and References

1. Book: Fonia . Athina . Baran . Robert . Lipner . Shari . Nail Disorders: Diagnosis and Management, An Issue of Dermatologic Clinics . 2021 . Elsevier . 978-0-323-70924-8 . 175-182 . https://books.google.com/books?id=0B0mEAAAQBAJ&pg=PA175 . en . Cutaneous paraneoplastic syndromes with nail involvement .
2. Book: James . William D. . Elston . Dirk . Treat . James R. . Rosenbach . Misha A. . Neuhaus . Isaac . Andrews' Diseases of the Skin: Clinical Dermatology . 2020 . Elsevier . Edinburgh . 978-0-323-54753-6 . 563-565 . 13th . https://books.google.com/books?id=UEaEDwAAQBAJ&pg=PA563 . en . 27. Genodermatoses and congenital anomalies .
3. Book: Chiesa-Fuxench . Zelma C. . Ramírez . Liliana . Sánchez . Néstor P. . Sánchez . Néstor P. . Atlas of Dermatology in Internal Medicine . 2011 . Springer Science & Business Media . New York . 978-1-4614-0687-7 . 66 . https://books.google.com/books?id=PACwY7Ms2F4C&pg=PA66 . en . Cutaneous manifestations of internal malignancy and paraneoplastic syndromes.
4. Gougerot, H. and Grupper, C., (1922). Dermatose érythémato-squameuse avec hyperkératose palmoplantaire, porectasies digitales et cancer de la langue latent. Paris Med, 43, pp.234-237
5. Bazex . A. . Griffiths . A. . Acrokeratosis paraneoplastica--a new cutaneous marker of malignancy . The British Journal of Dermatology . September 1980 . 103 . 3 . 301–306 . 10.1111/j.1365-2133.1980.tb07248.x . 7000146 . 0007-0963.