The Zee Cine Award Best Actor in a Comic Role is chosen by a jury organized by Zee Entertainment Enterprises, and the winner is announced at the ceremony.
| 2 | Govinda, Paresh Rawal, Riteish Deshmukh, Arshad Warsi, Kartik Aaryan |
| Year | Winner | Film | |
|---|---|---|---|
| 1998 | Chachi 420 | ||
| 1999 | Bade Miyan Chote Miyan | ||
| 2000 | Haseena Maan Jaayegi | ||
| 2001 | Hera Pheri | ||
| 2002 | Love Ke Liye Kuchh Bhi Karega | ||
| 2003 | Awara Paagal Deewana | ||
| 2004 | Munnabhai M.B.B.S. | ||
| 2005 | Masti | ||
| 2006 | Bluffmaster! | ||
| 2007 | Lage Raho Munna Bhai | ||
| 2008 | Bheja Fry | ||
| 2009 | Not Held | ||
| 2010 | Not Held | ||
| 2011 | Well Done Abba | ||
| 2012 | Pyaar Ka Punchnama | ||
| 2013 | Bol Bachchan | ||
| 2014 | Fukrey | ||
| 2015 | Varun Dhawan | Main Tera Hero | |
| 2016 | Bajrangi Bhaijaan | ||
| 2017 | Kapoor & Sons | ||
| 2019 | Sonu Ke Titu Ki Sweety | ||
| 2020 | Diljit Dosanjh and Kartik Aaryan | Good Newwz and Pati Patni Aur Woh | |
| 2021 | Not Held | ||
| 2022 | Not Held | ||
| 2023 | Jugjugg Jeeyo | ||
| 2024 | Dream Girl 2 | ||