| Office: | Member of the Virginia House of Delegates from Caroline County |
| Term Start: | December 1, 1897 |
| Term End: | December 6, 1899 |
| Predecessor: | W. L. Blanton |
| Successor: | Samuel E. Pitts |
| Office1: | President pro tempore of the Senate of Virginia |
| Term Start1: | March 1, 1875 |
| Term End1: | December 3, 1879 |
| Predecessor1: | Henry W. Thomas |
| Successor1: | Wyatt M. Elliott |
| Office2: | Member of the Virginia Senate for Hanover and Caroline |
| Term Start2: | December 6, 1871 |
| Term End2: | December 3, 1879 |
| Succeeded2: | Joseph A. Wingfield |
| Office3: | Member of the Virginia Senate for Caroline and Spotsylvania |
| Term Start3: | 1860 |
| Term End3: | December 4, 1865 |
| Preceded3: | F. W. Coleman |
| Birth Date: | 10 March 1828 |
| Death Place: | Milford, Virginia, U.S. |
| Party: | Democratic |
| Branch: | Confederate States Army |
| Serviceyears: | 1861–1865 |
| Rank: | Captain |
| Unit: | 30th Virginia Infantry |
| Battles: | American Civil War |
William DeJarnette Quesenberry (March 10, 1828 – December 8, 1901) was a Democratic politician who served as a member of the Virginia Senate, eventually rising to become president pro tempore of that body. He later served one term in the Virginia House of Delegates.[1]