| Villa Santa Maria | |
| Official Name: | Comune di Villa Santa Maria |
| Coordinates: | 41.95°N 35°W |
| Region: | Abruzzo |
| Province: | Chieti (CH) |
| Frazioni: | Contrada Madonna in Basilica, I Pagliai, Montebello, Contrada Poggio (La Stazione) |
| Mayor: | Giuseppe Finamore |
| Area Total Km2: | 16 |
| Population Footnotes: | [1] |
| Population Total: | 1450 |
| Population As Of: | 1 January 2008 |
| Population Demonym: | Villesi |
| Elevation M: | 390 |
| Saint: | St. Nicholas of Bari |
| Postal Code: | 66047 |
| Area Code: | 0872 |
| Istat: | 069102 |
| Fractions: | Atessa, Bomba, Borrello, Colledimezzo, Fallo, Montebello sul Sangro, Monteferrante, Montelapiano, Pennadomo, Pietraferrazzana, Roio del Sangro, Rosello |
| Fiscal Code: | M022 |
Villa Santa Maria (locally La Vìlle) is a town and comune in the province of Chieti, in the region of Abruzzo of southern Italy.
Some notable people from this town are Francis Caracciolo and Michele Mascitti.