| Villa San Secondo | |
| Official Name: | Comune di Villa San Secondo |
| Coordinates: | 45°N 16°W |
| Region: | Piedmont |
| Province: | Asti (AT) |
| Mayor: | Roberto Mussano |
| Area Total Km2: | 6.0 |
| Population Footnotes: | [1] |
| Population Total: | 402 |
| Population As Of: | 31 December 2014 |
| Population Demonym: | Villesi |
| Elevation M: | 287 |
| Postal Code: | 14020 |
| Area Code: | 0141 |
Villa San Secondo is a comune (municipality) in the Province of Asti in the Italian region Piedmont, located about 35km (22miles) east of Turin and about 12km (07miles) northwest of Asti.
Villa San Secondo borders the following municipalities: Castell'Alfero, Corsione, Cossombrato, Frinco, Montechiaro d'Asti, Montiglio Monferrato, and Tonco.