| Twentymile Creek | |
| Name Other: | Tributary to Lake Erie |
| Map Size: | 300 |
| Pushpin Map: | Pennsylvania#USA |
| Pushpin Map Size: | 300 |
| Pushpin Map Caption: | Location of Twentymile Creek mouth |
| Subdivision Type1: | Country |
| Subdivision Name1: | United States |
| Subdivision Type2: | State |
| Subdivision Name2: | Pennsylvania New York |
| Subdivision Type3: | Counties |
| Subdivision Name3: | Erie (PA) Chautauqua (NY) |
| Length: | 17.75miles[1] |
| Discharge1 Location: | Lake Erie |
| Discharge1 Avg: | 76.99cuft/s at mouth with Lake Erie[2] |
| Source1: | divide between Twentymile Creek and Chautauqua Creek |
| Source1 Location: | about 3 miles northeast of Sheldon Corners, NY[3] |
| Source1 Coordinates: | 42.2147°N -79.6425°W[4] |
| Source1 Elevation: | 1580feet |
| Mouth: | Lake Erie |
| Mouth Location: | about 4 miles northeast of Northeast, Pennsylvania near Orchard Beach |
| Mouth Coordinates: | 42.2631°N -79.7844°W |
| Mouth Elevation: | 574feet |
| Progression: | northwest |
| River System: | Lake Erie |
| Tributaries Left: | unnamed tributaries |
| Tributaries Right: | Belson Creek |
Twentymile Creek is a tributary of Lake Erie in Chautauqua County, New York and Erie County, Pennsylvania in the United States.[5]
Twentymile Creek joins Lake Erie near the community of Orchard Beach, Pennsylvania.[5]
Twentymile Creek is considered the largest stream in the eastern portion of Erie County. It is stocked annually with steelhead and trout by the Pennsylvania Fish Commission. Twentymile Creek is an approved trout water, so its fishing can be good throughout the year. Steelhead run into Twentymile all the way to New York, but not many anglers venture up that far to fish. New York State has undertaken efforts to stock brown trout in the upper reaches of Twentymile as well. The brown trout migrate out into Lake Erie and return to spawn. Access points along Route 20 are posted.