| Tres Palacios River | |
| Source1 Coordinates: | 29.1881°N -96.2803°W |
| Mouth Location: | Matagorda Bay |
| Mouth Coordinates: | 28.7575°N -96.1725°W |
| Subdivision Type1: | Country |
| Subdivision Name1: | United States |
Tres Palacios River is a river in Texas that rises near El Campo, flows in a southerly direction, and empties into Tres Palacios Bay, an arm of Matagorda Bay.