TRIM9 explained
Tripartite motif-containing protein 9 is a protein that in humans is encoded by the TRIM9 gene.[1] [2] [3]
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Its function has not been identified. Alternate splicing of this gene generates two transcript variants encoding different isoforms.[4]
Interactions
TRIM9 has been shown to interact with SNAP-25.
Further reading
- Nakajima D, Okazaki N, Yamakawa H, etal . Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. . DNA Res. . 9 . 3 . 99–106 . 2003 . 12168954 . 10.1093/dnares/9.3.99 . free .
- Dawson SJ, White LA . Treatment of Haemophilus aphrophilus endocarditis with ciprofloxacin. . J. Infect. . 24 . 3 . 317–20 . 1992 . 1602151 . 10.1016/S0163-4453(05)80037-4 .
- Ohara O, Nagase T, Ishikawa K, etal . Construction and characterization of human brain cDNA libraries suitable for analysis of cDNA clones encoding relatively large proteins. . DNA Res. . 4 . 1 . 53–9 . 1997 . 9179496 . 10.1093/dnares/4.1.53 . free .
- Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
- Ota T, Suzuki Y, Nishikawa T, etal . Complete sequencing and characterization of 21,243 full-length human cDNAs. . Nat. Genet. . 36 . 1 . 40–5 . 2004 . 14702039 . 10.1038/ng1285 . free .
- Gerhard DS, Wagner L, Feingold EA, etal . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 .
- Rual JF, Venkatesan K, Hao T, etal . Towards a proteome-scale map of the human protein-protein interaction network. . Nature . 437 . 7062 . 1173–8 . 2005 . 16189514 . 10.1038/nature04209 . 2005Natur.437.1173R . 4427026 .
Notes and References
- Reymond A, Meroni G, Fantozzi A, Merla G, Cairo S, Luzi L, Riganelli D, Zanaria E, Messali S, Cainarca S, Guffanti A, Minucci S, Pelicci PG, Ballabio A . The tripartite motif family identifies cell compartments . EMBO J . 20 . 9 . 2140–51 . May 2001 . 11331580 . 125245 . 10.1093/emboj/20.9.2140 .
- Li Y, Chin LS, Weigel C, Li L . Spring, a novel RING finger protein that regulates synaptic vesicle exocytosis . J Biol Chem . 276 . 44 . 40824–33 . Oct 2001 . 11524423 . 10.1074/jbc.M106141200 . free .
- Web site: Entrez Gene: TRIM9 tripartite motif-containing 9.
- Web site: Entrez Gene: TRIM9 tripartite motif-containing 9.
