TAAR3 explained

Putative trace amine-associated receptor 3 (TAAR3) is a human pseudogene with the gene symbol TAAR3P.^{[1] [2] [3] [4]} In other species such as mice, TAAR3 is a functional protein-coding gene that encodes a trace amine-associated receptor protein.

Isobutylamine is a known ligand of TAAR3 in mice associated with sexual behaviour in male mice.^[5]

Isopentylamine was identified as a ligand for murine TAAR3 eliciting aversive behavior.^[6]

See also

• Trace amine-associated receptor

Notes and References

1. Retrieved 28 November 2019
2. Lee DK, Lynch KR, Nguyen T, Im DS, Cheng R, Saldivia VR, Liu Y, Liu IS, Heng HH, Seeman P, George SR, O'Dowd BF, Marchese A . 6 . Cloning and characterization of additional members of the G protein-coupled receptor family . Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression . 1490 . 3 . 311–23 . February 2000 . 10684976 . 10.1016/s0167-4781(99)00241-9 .
3. Lindemann L, Ebeling M, Kratochwil NA, Bunzow JR, Grandy DK, Hoener MC . Trace amine-associated receptors form structurally and functionally distinct subfamilies of novel G protein-coupled receptors . Genomics . 85 . 3 . 372–85 . March 2005 . 15718104 . 10.1016/j.ygeno.2004.11.010 .
4. Web site: Entrez Gene: TAAR3 trace amine associated receptor 3.
5. Harmeier A, Meyer CA, Staempfli A, Casagrande F, Petrinovic MM, Zhang YP, Künnecke B, Iglesias A, Höner OP, Hoener MC . 6 . How Female Mice Attract Males: A Urinary Volatile Amine Activates a Trace Amine-Associated Receptor That Induces Male Sexual Interest . Frontiers in Pharmacology . 9 . 924 . 2018 . 30158871 . 6104183 . 10.3389/fphar.2018.00924 . free .
6. Liberles SD . Trace amine-associated receptors: ligands, neural circuits, and behaviors . Current Opinion in Neurobiology . 34 . 1–7 . October 2015 . 25616211 . 4508243 . 10.1016/j.conb.2015.01.001 .