| Event: | Men's 50 metre freestyle S4 |
| Games: | 2016 Summer |
| Venue: | Olympic Aquatics Stadium |
| Dates: | 17 September 2016 |
| Competitors: | 8 |
| Nations: | 7 |
| Gold: | Jo Giseong |
| Goldnpc: | KOR |
| Silver: | David Smétanine |
| Silvernpc: | FRA |
| Bronze: | Andrii Derevinskyi |
| Bronzenpc: | UKR |
| Prev: | 2012 |
| Next: | 2020 |
The men's 50 metre freestyle S4 event at the 2016 Paralympic Games took place on 17 September 2016, at the Olympic Aquatics Stadium. No heats were held. The swimmers with the eight fastest times advanced to the final.
18:26 17 September 2016:[1]
| Rank | Lane | Name | Nationality | Time | Notes | |
|---|---|---|---|---|---|---|
| 4 | 39.30 | |||||
| 5 | 40.58 | |||||
| 7 | 40.94 | |||||
| 4 | 2 | 41.21 | ||||
| 5 | 8 | 41.55 | ||||
| 6 | 3 | 41.99 | ||||
| 7 | 1 | 42.73 | ||||
| 8 | 6 | 43.51 |