Stomoxyn Explained

Stomoxyn is an insect antimicrobial peptide localised in the gut epithelium, which functions in killing a range of microorganisms, parasites and some viruses. In water, stomoxyn has a flexible random coil in structure, while in trifluoroethanol it adopts a stable helical structure. Structural similarities to the antimicrobial peptide cecropin A from Hyalophora cecropia suggest that it may function in a similar manner by disrupting the bacterial membrane.^[1]

Notes and References

1. Landon C, Meudal H, Boulanger N, Bulet P, Vovelle F . Solution structures of stomoxyn and spinigerin, two insect antimicrobial peptides with an alpha-helical conformation . Biopolymers . 81 . 2 . 92–103 . February 2006 . 16170803 . 10.1002/bip.20370 . 24098919 .