Ste24 endopeptidase explained

Ste24 endopeptidase is an enzyme.^[1] This enzyme catalyses the following chemical reaction

The peptide bond hydrolysed can be designated -C-aaX in which C is an S-isoprenylated cysteine residue, a is usually aliphatic and X is the C-terminal residue of the substrate protein, and may be any of several amino acids

This enzyme belongs to the peptidase family M48.

Notes and References

1. Tam A, Schmidt WK, Michaelis S . The multispanning membrane protein Ste24p catalyzes CAAX proteolysis and NH2-terminal processing of the yeast a-factor precursor . The Journal of Biological Chemistry . 276 . 50 . 46798–806 . December 2001 . 11581258 . 10.1074/jbc.m106150200 . free .