| South Seberang Perai District | |
| Official Name: | Malay: Daerah Seberang Perai Selatan |
| Settlement Type: | District of Penang |
| Subdivision Type: | Country |
| Subdivision Name: |  Malaysia |
| Subdivision Type1: | State |
| Subdivision Type2: | City |
| Subdivision Name2: | Seberang Perai |
| Seat: | Sungai Jawi |
| Leader Title1: | Local government |
| Leader Name1: | Seberang Perai City Council |
| Area Total Km2: | 243.2 |
| Population Total: | 184007 |
| Population As Of: | 2020 |
| Population Density Km2: | 756.6 |
| Postal Code Type: | Postal code |
| Postal Code: | 141xx–143xx |
The South Seberang Perai District is a district in Seberang Perai within the Malaysian state of Penang. The district covers the southern third of Seberang Perai. It borders Central Seberang Perai to the north, Kedah to the east and Perak to the south. The district, along with the North and Central Seberang Perai districts, falls under the jurisdiction of the Seberang Perai City Council.
The South Seberang Perai District is further divided into 18 subdivisions, officially known as mukims.
| Mukim 1 | 2,405 | 6.1 | 394 | |
| Mukim 2 | 1,510 | 4.8 | 315 | |
| Mukim 3 | 1,730 | 10.3 | 168 | |
| Mukim 4 | 9,884 | 13.2 | 749 | |
| Mukim 5 | 8,711 | 8.9 | 979 | |
| Mukim 6 | 7,679 | 9.1 | 844 | |
| Mukim 7 | 20,102 | 18.4 | 1,093 | |
| Mukim 8 | 2,382 | 15.3 | 156 | |
| Mukim 9 | 18,802 | 16.1 | 1,168 | |
| Mukim 10 | 9,033 | 21.6 | 418 | |
| Mukim 11 | 19,586 | 45.9 | 427 | |
| Mukim 12 | 10,290 | 9.6 | 1,072 | |
| Mukim 13 | 11,409 | 29.5 | 387 | |
| Mukim 14 | 22,990 | 13.9 | 1,654 | |
| Mukim 15 | 35,638 | 18.5 | 1,926 | |
| Mukim 16 | 191 | 1.2 | 159 | |
| Nibong Tebal | 1,425 | 0.7 | 2,036 | |
| Sungai Bakap | 240 | 0.1 | 2,400 |