| State: | SC |
| Type: | SC |
| Route: | 33 |
| Map: | SC 33 map.svg |
| Length Mi: | 19.360 |
| Length Round: | 3 |
| Length Ref: | [1] [2] |
| Direction A: | South |
| Terminus A: | in Orangeburg |
| Junction: |
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| Direction B: | North |
| Terminus B: | near Lone Star |
| Counties: | Orangeburg, Calhoun |
| Previous Type: | SC |
| Previous Route: | 31 |
| Next Type: | SC |
| Next Route: | 34 |
South Carolina Highway 33 (SC 33) is a 19.36adj=midNaNadj=mid state highway in the U.S. state of South Carolina. The highway connects Orangeburg with the Lone Star area, via Cameron.
SC 33 begins at an intersection with US 301/US 601/SC 4 (John C. Calhoun Drive) in Orangeburg within Orangeburg. Here, the highway continues as Andrew Dibble Street. It travels to the northeast and immediately passes Veterans Memorial Park. A few blocks later, it intersects US 178 Bus. (Broughton Street). It cuts through Memorial Park. On the southwestern corner of South Carolina State University is an intersection with US 21 Bus./US 601 (Magnolia Street). The highway travels along the southeastern edge of the university. It begins traveling along the Wilkinson Heights–Brookdale line. The highway then intersects US 21/US 178 (Chestnut Street/Whittaker Parkway). After leaving the city area, SC 33 travels through rural areas of the county, has an interchange with Interstate 26 (I-26), and passes the Bull Swamp Cemetery. Just before entering Cameron, it enters Calhoun County. In town, it intersects US 176 (Old State Road). The highway resumes a rural routing, including an intersection with SC 6, until it meets its northern terminus, an intersection with SC 267, near Lone Star.
| State: | SC |
| Type: | SC 1920 |
| Route: | 69 |
| Location: | Orangeburg–Cameron, South Carolina |
| Formed: | 1935 |
| Deleted: | 1938 |
South Carolina Highway 69 (SC 69) was a state highway that was established in either 1934 or 1935 on a path from what then was SC 4 in Orangeburg to a point to the east-northeast for about 5miles. In July 1936, it was extended to SC 31 (now US 176) in Cameron. In 1938, it was decommissioned and redesignated as part of SC 33.