| Siphokazi Mani-Lusithi | |
| Honorific-Suffix: | MPL |
| Office1: | Eastern Cape MEC for Public Works and Human Settlements |
| Premier1: | Oscar Mabuyane |
| Term Start1: | 21 June 2024 |
| Predecessor1: | Office established |
| Office2: | Eastern Cape MEC for Human Settlements |
| Premier2: | Oscar Mabuyane |
| Term Start2: | 16 August 2022 |
| Term End2: | 14 June 2024 |
| Predecessor2: | Nonceba Kontsiwe |
| Successor2: | Office abolished |
| Office3: | Eastern Cape MEC for Social Development |
| Premier3: | Oscar Mabuyane |
| Term Start3: | 29 May 2019 |
| Term End3: | 16 August 2022 |
| Predecessor3: | Pumza Dyantyi |
| Successor3: | Bukiwe Fanta |
| Office4: | Member of the Eastern Cape Provincial Legislature |
| Term Start4: | 22 May 2019 |
| Birth Date: | 19 July 1986 |
| Birth Place: | Steynsburg, South Africa |
| Nationality: | South African |
| Party: | African National Congress |
| Children: | 3 |
| Education: | Lawson Brown High School |
| Alma Mater: | University of Port Elizabeth University of Fort Hare |
Siphokazi Mani-Lusithi (born 19 July 1986) is a South African politician, currently a member of the Eastern Cape Provincial Legislature for the African National Congress, and the current Member of the Executive Council (MEC) responsible for Public Works and Human Settlements in the Eastern Cape provincial government. Mani-Lusithi previously served as the MEC for the Social Development and Human Settlements portfolios.
Mani-Lusithi was born on 19 July 1986 in Steynsburg in the former Cape Province. She matriculated from Lawson Brown High School in Port Elizabeth in 2003. She studied at the University of Port Elizabeth and the University of Fort Hare.[1] She is currently studying for a Bachelor of Administration degree from the University of South Africa.
Mani-Lusithi was involved in the African National Congress Youth League, the Young Communist League of South Africa, and student politics. She served as the provincial treasurer of the ANC youth league in the Eastern Cape and as the provincial chairperson of the South African Student Congress. She was also a member of the National Executive Committee (NEC) of the Young Communist League of South Africa.
Mani-Lusithi worked as a provincial manager on conferencing and electoral matters in the ANC provincial office. She was also a coordinator of an ANC PEC sub-committee. Prior to her election to the provincial legislature, Mani-Lusithi was an HR practitioner at the ANC Caucus Office at the provincial legislature.
In July 2023, Mani-Lusithi was elected provincial secretary of the African National Congress Women's League.[2]
Mani-Lusithi was elected to the Eastern Cape Provincial Legislature in the 2019 Eastern Cape provincial election.[3] She was then appointed Member of the Executive Council (MEC) for Social Development by the newly elected premier, Oscar Mabuyane.[4]
On 16 August 2022, Mani-Lusithi was appointed as the MEC for Human Settlements.[5] Following the 2024 general election, the Department of Public Works and Infrastructure was merged with the Department of Human Settlements; Mani-Lusithi was appointed MEC for the newly established department.[6]