| Serhiy Politylo | |
| Fullname: | Serhiy Olehovych Politylo |
| Birth Date: | 1989 1, df=yes |
| Birth Place: | Novovolynsk, Ukraine, Soviet Union |
| Height: | 1.65 m |
| Position: | Midfielder |
| Currentclub: | Chornomorets Odesa (assistant coach) |
| Youthyears1: | 2002–2005 |
| Youthclubs1: | RVUFK Kyiv |
| Youthyears2: | 2005 |
| Youthclubs2: | Vidradnyi Kyiv |
| Youthyears3: | 2005–2006 |
| Youthclubs3: | RVUFK Kyiv |
| Years1: | 2006–2013 |
| Caps1: | 99 |
| Goals1: | 7 |
| Years2: | 2008 |
| Clubs2: | → Dnister Ovidiopol (loan) |
| Caps2: | 12 |
| Goals2: | 1 |
| Years3: | 2013–2016 |
| Caps3: | 37 |
| Goals3: | 0 |
| Years4: | 2015–2016 |
| Clubs4: | → Volyn Lutsk (loan) |
| Caps4: | 27 |
| Goals4: | 1 |
| Years5: | 2017 |
| Clubs5: | Okzhetpes |
| Caps5: | 12 |
| Goals5: | 0 |
| Years6: | 2017 |
| Caps6: | 17 |
| Goals6: | 0 |
| Years7: | 2018 |
| Clubs7: | Adana Demirspor |
| Caps7: | 9 |
| Goals7: | 0 |
| Years8: | 2018–2021 |
| Caps8: | 74 |
| Goals8: | 9 |
| Years9: | 2021–2022 |
| Clubs9: | Lviv |
| Caps9: | 18 |
| Goals9: | 0 |
| Years10: | 2022–2023 |
| Caps10: | 24 |
| Goals10: | 0 |
| Years11: | 2023–2024 |
| Clubs11: | Tytan Odesa (amateur) |
| Nationalyears1: | 2004–2005 |
| Nationalcaps1: | 15 |
| Nationalgoals1: | 0 |
| Nationalyears2: | 2005–2006 |
| Nationalcaps2: | 8 |
| Nationalgoals2: | 0 |
| Nationalyears3: | 2006 |
| Nationalcaps3: | 2 |
| Nationalgoals3: | 0 |
| Nationalyears4: | 2007–2008 |
| Nationalcaps4: | 17 |
| Nationalgoals4: | 1 |
| Manageryears1: | 2024– |
| Managerclubs1: | Chornomorets Odesa (assistant) |
Serhiy Olehovych Politylo (uk|Сергій Олегович Політило; born 9 January 1989) is a Ukrainian professional football coach and a former midfielder. He is an assistant coach with Chornomorets Odesa.
He was promoted to the senior side from Chornomorets Reserves in November 2006.