| Senén Casas Regueiro | |
| Office: | Cuban Minister of Transportation |
| Term Start: | June (after 12 June) 1989 |
| Term End: | 6 August 1996 |
| Predecessor: | Diocles Torralba Gonzalez |
| Successor: | Álvaro Pérez Morales |
| Birth Date: | 30 July 1934 |
| Birth Place: | Bombí, El Salvador municipality |
| Death Date: | 6 August 1996 |
| Party: | Communist Party of Cuba |
Major General Senén Casas Regueiro (30 July 1934 in Bombí - 6 August 1996) was a Cuban politician. He was the Cuban Minister of Transportation from 1989 till his death. He was also the first deputy minister of defence and the chief of staff of the Cuban army. He was a brother of another Cuban politician, Julio Casas Regueiro.[1]
The railway station of Santiago de Cuba, rebuilt in 1997, was named after him.