| Santo Tomás, Baja California | |
| Pushpin Map: | Mexico |
| Pushpin Label Position: | bottom |
| Pushpin Label: | Santo Tomás |
| Pushpin Mapsize: | 280 |
| Pushpin Map Caption: | Location in Mexico |
| Subdivision Type: | Country |
| Subdivision Name: | Mexico |
| Subdivision Type1: | State |
| Subdivision Name1: | Baja California |
| Subdivision Type2: | Municipality |
| Subdivision Name2: | Ensenada |
| Timezone: | Northwest US Pacific |
| Utc Offset: | -8 |
| Timezone Dst: | Northwest |
| Utc Offset Dst: | -7 |
| Coordinates: | 30.8378°N -116.0572°W |
Santo Tomás a town in Ensenada Municipality, Baja California, on the Pacific Coast of Mexico. Santo Tomás is a primarily a wine-growing region, though it is increasingly a tourist destination.
It was originally the site of the Misión Santo Tomás de Aquino. After the mission was abandoned, it was taken as a post for the Mexican frontier garrison and for a time as the capital of the territory of Baja California. The town grew up east of the Mission site.
Santo Tomás is a wine-growing region, home to numerous vineyards and wineries. Since the rise in popularity of Valle de Guadalupe as a premier wine region in Baja California, Santo Tomás has begun to develop tourist accommodations, such as hotels and fine dining.