| Official Name: | Santo Antônio de Goiás |
| Settlement Type: | Municipality |
| Pushpin Map: | Brazil |
| Pushpin Map Caption: | Location in Brazil |
| Coordinates: | -16.4856°N -49.3089°W |
| Subdivision Type: | Country |
| Subdivision Name: | Brazil |
| Subdivision Type1: | Region |
| Subdivision Name1: | Central-West |
| Subdivision Type2: | State |
| Subdivision Name2: | Goiás |
| Subdivision Type3: | Mesoregion |
| Subdivision Type4: | Microregion |
| Subdivision Name4: | Goiânia Microregion |
| Subdivision Type5: | Metrop. region |
| Leader Title: | Mayor |
| Elevation M: | 762 |
| Area Total Km2: | 132.8 |
| Population Total: | 6,440 |
| Population As Of: | 2020 [1] |
| Population Density Km2: | auto |
| Timezone1: | BRT |
| Utc Offset1: | -3 |
| Postal Code Type: | Postal code |
| Postal Code: | 75374-000 |
| Area Code Type: | Area code |
Santo Antônio de Goiás is a municipality in central Goiás state, Brazil, located just north of the state capital, Goiânia.
Neighboring municipalities are:
Santo Antônio was a district of Goianira until it was dismembered in 1990.
The economy is based on subsistence agriculture, cattle raising, services, public administration, and small transformation industries.