| Santa Maria | |
| Settlement Type: | Administrative region |
| Official Name: | Região Administrativa de Santa Maria Administrative Region of Santa Maria |
| Mapsize: | 250px |
| Subdivision Type: | Country |
| Subdivision Type1: | Region |
| Subdivision Type2: | State |
| Subdivision Name: |  Brazil |
| Subdivision Name1: | Central-West |
| Subdivision Name2: | Federal District |
| Leader Title: | Regional administrator |
| Leader Name: | Marileide Romão |
| Established Title: | Established |
| Established Date: | 10 February 1991 |
| Area Total Km2: | 215.86 |
| Population Total: | 115607 |
| Population Density Km2: | auto |
| Timezone: | UTC-3 |
| Utc Offset: | -3 |
| Timezone Dst: | UTC-2 |
| Utc Offset Dst: | -2 |
| Coordinates: | -16.0153°N -48.0131°W |
| Area Code: | +55 61 |
| Postal Code Type: | Postal Code (CEP) |
Santa Maria is an administrative region in the Federal District in Brazil. Santa Maria was founded on February 10, 1991, receiving the status of administrative region, according to Law 348, of November 4, 1992.