| San Javier Department | |
| Native Name Lang: | es |
| Settlement Type: | Department |
| Mapsize: | 180px |
| Pushpin Map Caption: | Location of San Javier in Argentina |
| Coordinates: | -30.5833°N -116°W |
| Subdivision Type: | Country |
| Subdivision Name: |  Argentina |
| Subdivision Type1: | Province |
| Subdivision Name1: | Santa Fe |
| Seat Type: | Head town |
| Seat: | San Javier |
| Unit Pref: | Metric |
| Area Total Km2: | 6929 |
| Population Total: | 29912 |
| Population Density Km2: | auto |
| Timezone1: | ART |
| Utc Offset1: | -3 |
The San Javier Department (in Spanish, Departamento San Javier) is an administrative subdivision (departamento) of the . It is located on the northeast of the province, with its eastern border coinciding with the provincial border along the Paraná River.
The department's head town is the city of San Javier, which has over 15,000 inhabitants (more than half the population of the department). The department also includes the towns of Alejandra, Cacique Ariacaiquín, Colonia Durán, La Brava, and Romang.
San Javier Department borders the departments of Garay (south), San Justo (southwest), Vera (west), and General Obligado (north).
In Spanish.