| Official Name: | San Isidro |
| Pushpin Map: | Honduras |
| Pushpin Label Position: | right |
| Pushpin Mapsize: | 300 |
| Pushpin Map Caption: | Location in Honduras |
| Subdivision Type: | Country |
| Subdivision Name: | Honduras |
| Subdivision Type1: | Department |
| Subdivision Name1: | Intibucá |
| Area Total Km2: | 72 |
| Population As Of: | 2015 |
| Settlement Type: | Municipality |
| Population Total: | 4591 |
| Population Density Km2: | auto |
| Blank Name Sec1: | Municipality number |
| Blank Info Sec1: | 1011 |
| Coordinates: | 14.5667°N -95°W |
| Postal Code Type: | Postal code |
| Postal Code: | 14000 |
San Isidro (pronounced as /es/) is a municipality in the Honduran department of Intibucá.
At the time of the 2013 Honduras census, San Isidro municipality had a population of 4,387. Of these, 91.18% were Indigenous (90.77% Lenca), 7.20% Mestizo, 1.32% White and 0.30% Black or Afro-Honduran.[1]