| Saint-Mesmin | |
| Commune Status: | Commune |
| Image Coat Of Arms: | Blason Saint-Mesmin.svg |
| Arrondissement: | Nogent-sur-Seine |
| Canton: | Creney-près-Troyes |
| Insee: | 10353 |
| Postal Code: | 10280 |
| Mayor: | Patrice Masson[1] |
| Term: | 2022 - 2026 |
| Coordinates: | 48.4447°N 3.9264°W |
| Elevation M: | 89 |
| Area Km2: | 16.15 |
Saint-Mesmin (pronounced as /fr/) is a commune in the Aube department in north-central France.