| Saint-Côme | |
| Commune Status: | Commune |
| Image Coat Of Arms: | Blason ville fr Saint-Côme (Gironde).svg |
| Arrondissement: | Langon |
| Canton: | Le Sud-Gironde |
| Insee: | 33391 |
| Postal Code: | 33430 |
| Mayor: | Serge Mourlanne[1] |
| Term: | 2020 - 2026 |
| Intercommunality: | Bazadais |
| Coordinates: | 44.4269°N -0.1797°W |
| Elevation M: | 50 |
| Elevation Min M: | 42 |
| Elevation Max M: | 124 |
| Area Km2: | 5.96 |
Saint-Côme (pronounced as /fr/; oc|Sent Còrme) is a commune in the Gironde department in Nouvelle-Aquitaine in southwestern France.