SUV39H2 explained

Histone-lysine N-methyltransferase SUV39H2 is an enzyme that in humans is encoded by the SUV39H2 gene.^{[1] [2]}

Further reading

• Maruyama K, Sugano S . Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. . Gene . 138 . 1–2 . 171–4 . 1994 . 8125298 . 10.1016/0378-1119(94)90802-8 .
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, etal . Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library . Gene . 200 . 1–2 . 149–56 . 1997 . 9373149 . 10.1016/S0378-1119(97)00411-3 .
• Rea S, Eisenhaber F, O'Carroll D, etal . Regulation of chromatin structure by site-specific histone H3 methyltransferases . Nature . 406 . 6796 . 593–9 . 2000 . 10949293 . 10.1038/35020506 . 205008015 .
• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
• Ota T, Suzuki Y, Nishikawa T, etal . Complete sequencing and characterization of 21,243 full-length human cDNAs . Nat. Genet. . 36 . 1 . 40–5 . 2004 . 14702039 . 10.1038/ng1285 . free .
• Ait-Si-Ali S, Guasconi V, Fritsch L, etal . A Suv39h-dependent mechanism for silencing S-phase genes in differentiating but not in cycling cells . EMBO J. . 23 . 3 . 605–15 . 2005 . 14765126 . 10.1038/sj.emboj.7600074 . 1271807 .
• Frontelo P, Leader JE, Yoo N, etal . Suv39h histone methyltransferases interact with Smads and cooperate in BMP-induced repression . Oncogene . 23 . 30 . 5242–51 . 2004 . 15107829 . 10.1038/sj.onc.1207660 . free .
• Deloukas P, Earthrowl ME, Grafham DV, etal . The DNA sequence and comparative analysis of human chromosome 10 . Nature . 429 . 6990 . 375–81 . 2004 . 15164054 . 10.1038/nature02462 . 2004Natur.429..375D . free .
• Gerhard DS, Wagner L, Feingold EA, etal . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 .
• Rual JF, Venkatesan K, Hao T, etal . Towards a proteome-scale map of the human protein-protein interaction network . Nature . 437 . 7062 . 1173–8 . 2005 . 16189514 . 10.1038/nature04209 . 2005Natur.437.1173R . 4427026 .
• Yoon KA, Hwangbo B, Kim IJ, etal . Novel polymorphisms in the SUV39H2 histone methyltransferase and the risk of lung cancer . Carcinogenesis . 27 . 11 . 2217–22 . 2006 . 16774942 . 10.1093/carcin/bgl084 . free .

Notes and References

1. O'Carroll D, Scherthan H, Peters AH, Opravil S, Haynes AR, Laible G, Rea S, Schmid M, Lebersorger A, Jerratsch M, Sattler L, Mattei MG, Denny P, Brown SD, Schweizer D, Jenuwein T . Isolation and characterization of Suv39h2, a second histone H3 methyltransferase gene that displays testis-specific expression . Mol Cell Biol . 20 . 24 . 9423–33 . Dec 2000 . 11094092 . 102198 . 10.1128/MCB.20.24.9423-9433.2000 .
2. Web site: Entrez Gene: SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila).