SPRR1A explained

Cornifin-A is a protein that in humans is encoded by the SPRR1A gene.^{[1] [2]}

Further reading

• Greco MA, Lorand L, Lane WS, Baden HP, Parameswaran KN, Kvedar JC . The pancornulins: a group of small proline rich-related cornified envelope precursors with bifunctional capabilities in isopeptide bond formation . The Journal of Investigative Dermatology . 104 . 2 . 204–10 . February 1995 . 7829876 . 10.1111/1523-1747.ep12612759 . free .
• Robinson PA, Marley JJ, High AS, Hume WJ . Differential expression of protease inhibitor and small proline-rich protein genes between normal human oral tissue and odontogenic keratocysts . Archives of Oral Biology . 39 . 3 . 251–9 . March 1994 . 8018055 . 10.1016/0003-9969(94)90051-5 .
• Fujimoto W, Nakanishi G, Arata J, Jetten AM . Differential expression of human cornifin alpha and beta in squamous differentiating epithelial tissues and several skin lesions . The Journal of Investigative Dermatology . 108 . 2 . 200–4 . February 1997 . 9008234 . 10.1111/1523-1747.ep12334240 . free .
• Robinson NA, Lapic S, Welter JF, Eckert RL . S100A11, S100A10, annexin I, desmosomal proteins, small proline-rich proteins, plasminogen activator inhibitor-2, and involucrin are components of the cornified envelope of cultured human epidermal keratinocytes . The Journal of Biological Chemistry . 272 . 18 . 12035–46 . May 1997 . 9115270 . 10.1074/jbc.272.18.12035 . free .
• Reddy SP, Konkin T, Wu R . Structure and organization of the genes encoding mouse small proline-rich proteins, mSPRR1A and 1B . Gene . 224 . 1–2 . 59–66 . December 1998 . 9931436 . 10.1016/S0378-1119(98)00507-1 .
• Candi E, Tarcsa E, Idler WW, Kartasova T, Marekov LN, Steinert PM . Transglutaminase cross-linking properties of the small proline-rich 1 family of cornified cell envelope proteins. Integration with loricrin . The Journal of Biological Chemistry . 274 . 11 . 7226–37 . March 1999 . 10066784 . 10.1074/jbc.274.11.7226 . free .
• Lee CH, Marekov LN, Kim S, Brahim JS, Park MH, Steinert PM . Small proline-rich protein 1 is the major component of the cell envelope of normal human oral keratinocytes . FEBS Letters . 477 . 3 . 268–72 . July 2000 . 10908733 . 10.1016/S0014-5793(00)01806-8 . free .
• Hartley JL, Temple GF, Brasch MA . DNA cloning using in vitro site-specific recombination . Genome Research . 10 . 11 . 1788–95 . November 2000 . 11076863 . 310948 . 10.1101/gr.143000 .
• Cabral A, Voskamp P, Cleton-Jansen AM, South A, Nizetic D, Backendorf C . Structural organization and regulation of the small proline-rich family of cornified envelope precursors suggest a role in adaptive barrier function . The Journal of Biological Chemistry . 276 . 22 . 19231–7 . June 2001 . 11279051 . 10.1074/jbc.M100336200 . free .
• Bonilla IE, Tanabe K, Strittmatter SM . Small proline-rich repeat protein 1A is expressed by axotomized neurons and promotes axonal outgrowth . The Journal of Neuroscience . 22 . 4 . 1303–15 . February 2002 . 10.1523/JNEUROSCI.22-04-01303.2002 . 11850458 . 6757578 .

Notes and References

1. Gibbs S, Fijneman R, Wiegant J, van Kessel AG, van De Putte P, Backendorf C . Molecular characterization and evolution of the SPRR family of keratinocyte differentiation markers encoding small proline-rich proteins . Genomics . 16 . 3 . 630–7 . June 1993 . 8325635 . 10.1006/geno.1993.1240 .
2. Web site: Entrez Gene: SPRR1A small proline-rich protein 1A.