SOX30 explained

SRY (sex determining region Y)-box 30 is a protein that in humans is encoded by the SOX30 gene.^[1]

Function

This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may be involved in the differentiation of developing male germ cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013].

Further reading

• 15019997. 2004. Koopman. P. Origin and diversity of the SOX transcription factor gene family: Genome-wide analysis in Fugu rubripes. Gene. 328. 177–86. Schepers. G. Brenner. S. Venkatesh. B. 10.1016/j.gene.2003.12.008.
• 10359848. 1999. Osaki. E. Identification of a novel Sry-related gene and its germ cell-specific expression. Nucleic Acids Research. 27. 12. 2503–10. Nishina. Y. Inazawa. J. Copeland. N. G.. Gilbert. D. J.. Jenkins. N. A.. Ohsugi. M. Tezuka. T. Yoshida. M. Semba. K. 148454 . 10.1093/nar/27.12.2503.
• 18436822. 2008. Fan. B. J.. Gene expression profiles of human trabecular meshwork cells induced by triamcinolone and dexamethasone. Investigative Ophthalmology & Visual Science. 49. 5. 1886–97. Wang. D. Y.. Tham. C. C.. Lam. D. S.. Pang. C. P.. 10.1167/iovs.07-0414.
• 11678506. 2000. Bullejos. Díaz de la Guardia R. M. HMG-box sequences from microbats homologous to the human SOX30 HMG-box. Genetica. 110. 2. 157–62. Barragán. M. J.. Sánchez. A. 10.1023/A:1017914005677. 16100625.

Notes and References

1. Web site: Entrez Gene: SRY (sex determining region Y)-box 30. 2014-05-29 .