SNAPC1 explained

snRNA-activating protein complex subunit 1 is a protein that in humans is encoded by the SNAPC1 gene.^{[1] [2]}

Interactions

SNAPC1 has been shown to interact with SNAPC4,^[3] SNAPC3^{[3] [4]} and Retinoblastoma protein.^[5]

Further reading

• Henry RW . Sadowski CL . Kobayashi R . Hernandez N . A TBP-TAF complex required for transcription of human snRNA genes by RNA polymerase II and III . Nature . 374 . 6523 . 653–6 . 1995 . 7715707 . 10.1038/374653a0 . 1995Natur.374..653H . 4325527 .
• Yoon JB . Roeder RG . Cloning of two proximal sequence element-binding transcription factor subunits (gamma and delta) that are required for transcription of small nuclear RNA genes by RNA polymerases II and III and interact with the TATA-binding protein . Mol. Cell. Biol. . 16 . 1 . 1–9 . 1996 . 8524284 . 10.1016/S1569-2558(08)60061-2 . 230972 . Advances in Molecular and Cell Biology . 978-0-7623-0143-0 .
• Henry RW, Ma B, Sadowski CL, etal . Cloning and characterization of SNAP50, a subunit of the snRNA-activating protein complex SNAPc . EMBO J. . 15 . 24 . 7129–36 . 1997 . 10.1002/j.1460-2075.1996.tb01104.x . 9003788 . 452539 .
• Ma B . Hernandez N . A map of protein-protein contacts within the small nuclear RNA-activating protein complex SNAPc . J. Biol. Chem. . 276 . 7 . 5027–35 . 2001 . 11056176 . 10.1074/jbc.M009301200 . free.
• Hirsch HA . Gu L . Henry RW . The Retinoblastoma Tumor Suppressor Protein Targets Distinct General Transcription Factors To Regulate RNA Polymerase III Gene Expression . Mol. Cell. Biol. . 20 . 24 . 9182–91 . 2001 . 11094070 . 10.1128/MCB.20.24.9182-9191.2000 . 102176 .
• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
• Hinkley CS, Hirsch HA, Gu L, etal . The small nuclear RNA-activating protein 190 Myb DNA binding domain stimulates TATA box-binding protein-TATA box recognition . J. Biol. Chem. . 278 . 20 . 18649–57 . 2003 . 12621023 . 10.1074/jbc.M204247200 . free .
• Gerhard DS, Wagner L, Feingold EA, etal . The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 .
• Gu L . Esselman WJ . Henry RW . Cooperation between small nuclear RNA-activating protein complex (SNAPC) and TATA-box-binding protein antagonizes protein kinase CK2 inhibition of DNA binding by SNAPC . J. Biol. Chem. . 280 . 30 . 27697–704 . 2005 . 15955816 . 10.1074/jbc.M503206200 . free .
• Rual JF, Venkatesan K, Hao T, etal . Towards a proteome-scale map of the human protein-protein interaction network . Nature . 437 . 7062 . 1173–8 . 2005 . 16189514 . 10.1038/nature04209 . 2005Natur.437.1173R . 4427026 .

Notes and References

1. Maeng JH . Yoon JB . The human PTFgamma/SNAP43 gene: structure, chromosomal location, and identification of a VNTR in 5'-UTR . J Biochem . 124 . 1 . 23–7 . September 1998 . 9644240 . 10.1093/oxfordjournals.jbchem.a022085.
2. Web site: Entrez Gene: SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa.
3. Ma . B . Hernandez N . February 2001 . A map of protein-protein contacts within the small nuclear RNA-activating protein complex SNAPc . J. Biol. Chem. . 276 . 7 . 5027–35 . United States. 0021-9258. 11056176 . 10.1074/jbc.M009301200 . free.
4. Henry . R W . Ma B . Sadowski C L . Kobayashi R . Hernandez N . Dec 1996 . Cloning and characterization of SNAP50, a subunit of the snRNA-activating protein complex SNAPc . EMBO J. . 15 . 24 . 7129–36 . ENGLAND. 10.1002/j.1460-2075.1996.tb01104.x . 0261-4189. 9003788 . 452539 .
5. Hirsch . H A . Gu L . Henry R W . Dec 2000 . The Retinoblastoma Tumor Suppressor Protein Targets Distinct General Transcription Factors To Regulate RNA Polymerase III Gene Expression . Mol. Cell. Biol. . 20 . 24 . 9182–91 . UNITED STATES. 0270-7306. 11094070 . 10.1128/MCB.20.24.9182-9191.2000 . 102176 .