SB-200646 explained

SB-200646 is a 5-HT2 receptor antagonist with anxiolytic properties in rats. It was the first 5-HT2 antagonist discovered to exhibit selectivity for the 5-HT2C/2B receptors over the 5-HT2A receptor.[1]

Notes and References

  1. Kennett GA, Wood MD, Glen A, Grewal S, Forbes I, Gadre A, Blackburn TP . In vivo properties of SB 200646A, a 5-HT2C/2B receptor antagonist . British Journal of Pharmacology . 111 . 3 . 797–802 . March 1994 . 7912626 . 1910094 . 10.1111/j.1476-5381.1994.tb14808.x .

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