| Honorific-Prefix: | Hon. |
| S. M. Chandrasena | |
| Native Name: | සමරකෝන් මුදියන්සේලාගේ චන්ද්රසේන சமரகோன் முடியன்சேலாகே சந்திரசேனா |
| Honorific-Suffix: | MP |
| Office: | Minister of Agriculture |
| Term Start: | 2004 |
| Term End: | 2007 |
| Office2: | Non-Cabinet Minister of Nation Building |
| Term Start2: | 2007 |
| Term End2: | 2010 |
| Office3: | Deputy Minister of Irrigation & Water Resources Management |
| Term Start3: | 2010 |
| Term End3: | 12 January 2015 |
| Constituency Mp4: | Anuradhapura District |
| Parliament4: | Sri Lanka |
| Term Start4: | 2001 |
| Birth Date: | 3 May 1955 |
| Nationality: | Sri Lankan |
| Party: | Sri Lanka Freedom Party |
| Otherparty: | United People's Freedom Alliance |
| Occupation: | Agriculturist |
Samarakoon Mudiyanselage Chandrasena (born May 3, 1955) is a Sri Lankan politician, a member of the Parliament of Sri Lanka and a government minister. He has one child. His brother is former chief minister of North Central province, S. M. Ranjith. He is a famous politician in Anuradhapura District.