| Sère-Rustaing | |
| Commune Status: | Commune |
| Image Coat Of Arms: | Blason ville fr Sère-Rustaing (65).svg |
| Arrondissement: | Tarbes |
| Canton: | Les Coteaux |
| Insee: | 65423 |
| Postal Code: | 65220 |
| Intercommunality: | Pays de Trie et Magnoac |
| Coordinates: | 43.2631°N 0.295°W |
| Elevation M: | 400 |
| Elevation Min M: | 330 |
| Elevation Max M: | 456 |
| Area Km2: | 5.29 |
Sère-Rustaing (pronounced as /fr/; oc|Cèra d'Arrostanh) is a commune in the Hautes-Pyrénées department in south-western France.