| Official Name: | Ruisi |
| Native Name: | რუისი |
| Pushpin Map: | Georgia (country) |
| Pushpin Label Position: | bottom |
| Pushpin Mapsize: | 300 |
| Pushpin Map Caption: | Location in Georgia |
| Subdivision Type: | Country |
| Subdivision Type1: | Region |
| Subdivision Name: | Georgia |
| Subdivision Name1: | Shida Kartli |
| Subdivision Type2: | Municipality |
| Subdivision Name2: | Kareli |
| Population As Of: | 2014 |
| Population Total: | 5139 |
| Timezone: | Georgian Time |
| Utc Offset: | +4 |
| Coordinates: | 42.0344°N 43.9569°W |
| Elevation M: | 670 |
Ruisi (Georgian: რუისი) is a village in Kareli District of Shida Kartli region of the Republic of Georgia. Situated about 3 km from the district administrative center Kareli and 10 km from the city of Gori, Ruisi is one of the oldest centers of Christianity in Georgia. The bishop of Ruisi was mentioned already in the beginning of 6th century. The Ruisi cathedral dates back to the 8th century.[1]