| Jurisdiction: | Diocese |
| Ekwulobia | |
| Latin: | Dioecesis Ekvulobianus |
| Country: | Nigeria |
| Territory: | Anambra State |
| Metropolitan: | Archbishop of Onitsha |
| Area Km2: | 675.8 |
| Population: | 984,415 |
| Population As Of: | 2020 |
| Catholics: | 602,115 |
| Parishes: | 82 |
| Denomination: | Catholic Church |
| Sui Iuris Church: | Latin Church |
| Rite: | Roman Rite |
| Established: | 5 March 2020 |
| Cathedral: | St. Joseph's Catholic Church |
| Bishop: | Peter Ebere Okpaleke |
| Suffragan: | for one --> |
| Archdeacon: | for one--> |
The Diocese of Ekwulobia is a Latin Church ecclesiastical jurisdiction or diocese of the Catholic Church located in Anambra State, Nigeria. It is a suffragan diocese in the ecclesiastical province of the metropolitan Onitsha.
The first Bishop of Ekwulobia, Peter Ebere Okpaleke, was installed on 29 April 2020.