RRAGC explained

Ras-related GTP binding C, also known as RRAGC, is a protein which in humans is encoded by the RRAGC gene.^{[1] [2]}

RRAGC is a monomeric guanine nucleotide-binding protein, or G protein. By binding GTP or GDP, small G proteins act as molecular switches in numerous cell processes and signaling pathways.^[1]

Interactions

RRAGC has been shown to interact with RRAGA.^[3]

Further reading

• Horwitz MS . Adenovirus immunoregulatory genes and their cellular targets . Virology . 279 . 1 . 1–8 . Jan 2001 . 11145883 . 10.1006/viro.2000.0738 . free .
• Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M . Towards a proteome-scale map of the human protein-protein interaction network . Nature . 437 . 7062 . 1173–8 . Oct 2005 . 16189514 . 10.1038/nature04209 . 2005Natur.437.1173R . 4427026 .
• Sekiguchi T, Todaka Y, Wang Y, Hirose E, Nakashima N, Nishimoto T . A novel human nucleolar protein, Nop132, binds to the G proteins, RRAG A/C/D . The Journal of Biological Chemistry . 279 . 9 . 8343–50 . Feb 2004 . 14660641 . 10.1074/jbc.M305935200 . free .
• Sekiguchi T, Hirose E, Nakashima N, Ii M, Nishimoto T . Novel G proteins, Rag C and Rag D, interact with GTP-binding proteins, Rag A and Rag B . The Journal of Biological Chemistry . 276 . 10 . 7246–57 . Mar 2001 . 11073942 . 10.1074/jbc.M004389200 . free .

Notes and References

1. Web site: Entrez Gene: RRAGC Ras-related GTP binding C.
2. Sekiguchi T, Hirose E, Nakashima N, Ii M, Nishimoto T . Novel G proteins, Rag C and Rag D, interact with GTP-binding proteins, Rag A and Rag B . The Journal of Biological Chemistry . 276 . 10 . 7246–57 . Mar 2001 . 11073942 . 10.1074/jbc.M004389200 . free .
3. Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M . Huda Zoghbi. Towards a proteome-scale map of the human protein-protein interaction network . Nature . 437 . 7062 . 1173–8 . Oct 2005 . 16189514 . 10.1038/nature04209 . 2005Natur.437.1173R. 4427026.