RNF13 explained

RING finger protein 13 is a protein that in humans is encoded by the RNF13 gene.^[1]

The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. The specific function of this gene has not yet been determined. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.

Further reading

• Kimura K, Wakamatsu A, Suzuki Y, etal . Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. . Genome Res. . 16 . 1 . 55–65 . 2006 . 16344560 . 10.1101/gr.4039406 . 1356129 .
• Wesselkamper SC, McDowell SA, Medvedovic M, etal . The role of metallothionein in the pathogenesis of acute lung injury. . Am. J. Respir. Cell Mol. Biol. . 34 . 1 . 73–82 . 2006 . 16166738 . 10.1165/rcmb.2005-0248OC . 2644192 .
• Gerhard DS, Wagner L, Feingold EA, etal . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 .
• Ota T, Suzuki Y, Nishikawa T, etal . Complete sequencing and characterization of 21,243 full-length human cDNAs. . Nat. Genet. . 36 . 1 . 40–5 . 2004 . 14702039 . 10.1038/ng1285 . free .
• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
• Yu W, Andersson B, Worley KC, etal . Large-scale concatenation cDNA sequencing. . Genome Res. . 7 . 4 . 353–8 . 1997 . 9110174 . 10.1101/gr.7.4.353. 139146 .
• Andersson B, Wentland MA, Ricafrente JY, etal . A "double adaptor" method for improved shotgun library construction. . Anal. Biochem. . 236 . 1 . 107–13 . 1996 . 8619474 . 10.1006/abio.1996.0138 .
• Tranque P, Crossin KL, Cirelli C, etal . Identification and characterization of a RING zinc finger gene (C-RZF) expressed in chicken embryo cells. . Proc. Natl. Acad. Sci. U.S.A. . 93 . 7 . 3105–9 . 1996 . 8610176 . 10.1073/pnas.93.7.3105. 39769 . 1996PNAS...93.3105T . free .

Notes and References

1. Web site: Entrez Gene: RNF13 ring finger protein 13.