| Puisseguin | |
| Commune Status: | Commune |
| Image Coat Of Arms: | Blason ville fr Puisseguin (Gironde).svg |
| Arrondissement: | Libourne |
| Canton: | Le Nord-Libournais |
| Insee: | 33342 |
| Postal Code: | 33570 |
| Mayor: | Jean Michel Pasquon[1] |
| Term: | 2020 - 2026 |
| Intercommunality: | Grand Saint-Émilionnais |
| Coordinates: | 44.9244°N -0.0719°W |
| Elevation M: | 83 |
| Elevation Min M: | 38 |
| Elevation Max M: | 108 |
| Area Km2: | 17.25 |
Puisseguin (pronounced as /fr/; oc|Puègseguin) is a commune in the Gironde department in Nouvelle-Aquitaine in southwestern France. It is around 15 km east of Libourne.
In October 2015, 43 people died in a crash between a bus and a lorry.[2]
Located in the Pays du Libournais.
The neighboring towns are Lussac in the north, Tayac in the extreme north-east for about 250 meters, Saint-Cibard to the East, Saint-Philippe-d'Aiguille at the South-East, Saint-Genès-de-Castillon at the South and Montagne in the west.