| Portuguesa River | |
| Subdivision Type1: | Country |
| Length: | 600km (400miles) |
| Basin Size: | 80000km2 |
The Portuguesa River (Spanish: Río Portuguesa, also Río la Portuguesa, Río de la Portuguesa) is a river of Venezuela. It is part of the Orinoco River basin, and is a tributary of the Apure River (which is, in turn, a tributary of the Orinoco).
Legend has it that the river's name originated from a woman from Portugal who drowned in its waters. In turn, the river's name is the origin of the name of the Venezuelan state of Portuguesa.