Pinosylvin synthase explained

In enzymology, a pinosylvin synthase is an enzyme that catalyzes the chemical reaction

3 malonyl-CoA + cinnamoyl-CoA

4 CoA + pinosylvin + 4 CO₂

Thus, the two substrates of this enzyme are malonyl-CoA and cinnamoyl-CoA, whereas its 3 products are CoA, pinosylvin, and CO₂.^[1]

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is malonyl-CoA:cinnamoyl-CoA malonyltransferase (cyclizing). Other names in common use include stilbene synthase, and pine stilbene synthase.^[2] This enzyme participates in phenylpropanoid biosynthesis.^[2]

Notes and References

1. Gehlert R . 1990 . Stilbene Synthase from Seedlings of Pinus sylvestris : Purification and Induction in Response to Fungal Infection . Molecular Plant-Microbe Interactions . 3 . 6 . 444 . 10.1094/MPMI-3-444 .
2. Valletta A, Iozia LM, Leonelli F . Impact of Environmental Factors on Stilbene Biosynthesis . Plants . 10 . 1 . 90 . January 2021 . 33406721 . 10.3390/plants10010090 . 7823792 . free .