Patrik Rorsman Explained

Honorific Prefix:Professor
Patrik Rorsman
Birth Date:1959 5, df=yes
Birth Place:Lund, Sweden
Nationality:Swedish
Alma Mater:Uppsala University
Thesis Title:Patch-clamp studies on pancreatic glucagon- and insulin-secreting cells
Thesis Url:http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-114628
Thesis Year:1986
Doctoral Advisor:Bert Sakmann

Patrik Rorsman (born 1959) is a Swedish scientist who is Professor of Diabetic Medicine at the Oxford Centre for Diabetes, Endocrinology and Metabolism (OCDEM), in the Radcliffe Department of Medicine at the University of Oxford[1] and a fellow of Harris Manchester College, Oxford.[2] [3]

Education

Rorsman was educated at Uppsala University in Sweden where he was awarded a PhD under the supervision of Nobel laureate Bert Sakmann in 1986 for patch clamp studies of pancreatic cells and their secretion of glucagon and insulin.[4]

Career

Rorsman was for short time the Canadian Excellence in Research Chair (CERC) in Diabetes[1] [5] [6] at the University of Alberta in Edmonton, before being reappointed a Professor at the University of Oxford in 2011.[1]

Research

Rorsman's research investigates exocytosis, ion channels and diabetes mellitus type 2.[7] [8] [9] [10] [11] [12] [13] [14] [15] His research been funded by the Medical Research Council (MRC),[16] the Royal Society, the Wolfson Foundation, the Knut and Alice Wallenberg Foundation,[17] the Wellcome Trust and the Government of Canada.[3]

Awards and honours

Rorsman was elected a Fellow of the Royal Society (FRS) in 2014. His nomination reads:

Rorsman was elected a Fellow of the Academy of Medical Sciences (FMedSci) in 2010. His nomination reads:

Rorsman was awarded the Minkowski Prize in 1996, the Göran Gustafsson Prize in 2003 and the Albert Renold Prize in 2013.

Notes and References

  1. 10.1038/nj7428-301a. Turning point: Patrik Rorsman. Nature. 492. 7428. 301. 2012. Gewin . V. . free.
  2. http://www.hmc.ox.ac.uk/pages/default.asp?id=16&sID=86&cP=298 Professor Patrik Rorsman, Harris Manchester College
  3. http://news.nationalpost.com/2012/11/14/they-suffer-from-the-climate-research-scientist-leaves-10m-edmonton-research-grant-behind-returns-to-england/ Patrik Rorsman leaves $10M Edmonton research grant behind, returns to England
  4. PhD . Patrik. Rorsman . Patch-clamp studies on pancreatic glucagon- and insulin-secreting cells . Uppsala University. 1986 . Patrik Rorsman.
  5. https://labandfield.wordpress.com/2013/05/06/the-value-of-the-canada-excellence-research-chairs-cerc-program/ The value of the Canada Excellence Research Chairs (CERC) program
  6. , University of Alberta
  7. 10.1016/0079-6107(89)90013-8. Electrophysiology of the pancreatic β-cell. Progress in Biophysics and Molecular Biology. 54. 2. 87–143. 1989. Ashcroft . F. M. . Frances Ashcroft. Rorsman . P. . Patrik Rorsman. 2484976. free.
  8. 10.1038/nature03076. A pancreatic islet-specific microRNA regulates insulin secretion. Nature. 432. 7014. 226–30. 2004. Poy . M. N. . Eliasson . L. . Krutzfeldt . J. . Kuwajima . S. . Ma . X. . MacDonald . P. E. . Pfeffer . S. B. . Tuschl . T. . Rajewsky . N. . Rorsman . P. . Stoffel . M. . 15538371. 2004Natur.432..226P. 4415988.
  9. 10.1007/s00125-003-1153-1. Insulin granule dynamics in pancreatic beta cells. Diabetologia. 46. 8. 1029–45. 2003. Rorsman . P.. Renstrom . E.. 12879249. free.
  10. 10.1038/363356a0. Calcium-independent potentiation of insulin release by cyclic AMP in single β-cells. Nature. 363. 6427. 356–358. 1993. Ämmälä . C. . Ashcroft . F. M. . Rorsman . P. . 7684514. 1993Natur.363..356A. 4341009.
  11. 10.1038/341233a0. Glucose-inhibition of glucagon secretion involves activation of GABAA-receptor chloride channels. Nature. 341. 6239. 233–6. 1989. Rorsman . P. . Berggren . P. O. . Bokvist . K. . Ericson . H. . Möhler . H. . Östenson . C. G. R. . Smith . P. A. . 2550826. 1989Natur.341..233R. 699135.
  12. 10.1098/rstb.2005.1762. Glucose-sensing mechanisms in pancreatic -cells. Philosophical Transactions of the Royal Society B: Biological Sciences. 360. 1464. 2211–25. 2005. MacDonald . P. E.. Joseph . J. W.. Rorsman . P.. 1569593 . 16321791.
  13. Gerken . T. . Girard . C. A. . Tung . Y. -C. L. . Webby . C. J. . Saudek . V. . Hewitson . K. S. . Yeo . G. S. H. . McDonough . M. A. . Cunliffe . S. . McNeill . 10.1126/science.1151710 . L. A. . Galvanovskis . J. . Rorsman . P. . Patrik Rorsman. Robins . P. . Prieur . X. . Coll . A. P. . Ma . M. . Jovanovic . Z. . Farooqi . I. S.. Sadaf Farooqi . Sedgwick . B. . Barroso . I. . Lindahl . T. . Tomas Lindahl. Ponting . C. P. . Chris Ponting. Ashcroft . F. M. . Frances Ashcroft. O'Rahilly . S. . Stephen O'Rahilly. Schofield . C. J. . Christopher J. Schofield . The Obesity-Associated FTO Gene Encodes a 2-Oxoglutarate-Dependent Nucleic Acid Demethylase . Science . 318 . 5855 . 1469–1472 . 2007 . 17991826. 2668859 . 2007Sci...318.1469G .
  14. , University of Oxford
  15. , Scandinavian Physiological Society
  16. http://gtr.rcuk.ac.uk/person/5ADEBA84-AFD6-4FAC-B1B6-16B2436E5CBA UK Government research grants awarded to Patrik Rorsman
  17. http://www.akademiliv.se/en/2012/12/9066/ Wallenberg researcher aiming to solve the riddle of diabetes

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