Protein phosphatase 1 regulatory subunit 12c explained

Protein phosphatase 1 regulatory subunit 12C is a protein that in humans is encoded by the PPP1R12C gene.^[1]

Function

The gene encodes a subunit of myosin phosphatase. The encoded protein regulates the catalytic activity of protein phosphatase 1 delta and assembly of the actin cytoskeleton. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Further reading

• Surks HK, Richards CT, Mendelsohn ME . Myosin phosphatase-Rho interacting protein. A new member of the myosin phosphatase complex that directly binds RhoA . J. Biol. Chem. . 278 . 51 . 51484–93 . 2003 . 14506264 . 10.1074/jbc.M305622200 . free .

Notes and References

1. Web site: Entrez Gene: Protein phosphatase 1 regulatory subunit 12C. 2016-11-14.