PLXNB3 explained

Plexin-B3 is a protein that in humans is encoded by the PLXNB3 gene.^{[1] [2]}

Interactions

PLXNB3 has been shown to interact with ARHGEF11.^{[3] [4]}

Further reading

• Sandoval N, Bauer D, Brenner V, Coy JF, Drescher B, Kioschis P, Korn B, Nyakatura G, Poustka A, Reichwald K, Rosenthal A, Platzer M . The genomic organization of a human creatine transporter (CRTR) gene located in Xq28 . Genomics . 35 . 2 . 383–5 . Jul 1996 . 8661155 . 10.1006/geno.1996.0373 .
• Brenner V, Nyakatura G, Rosenthal A, Platzer M . Genomic organization of two novel genes on human Xq28: compact head to head arrangement of IDH gamma and TRAP delta is conserved in rat and mouse . Genomics . 44 . 1 . 8–14 . Aug 1997 . 9286695 . 10.1006/geno.1997.4822 .
• Nagase T, Ishikawa K, Kikuno R, Hirosawa M, Nomura N, Ohara O . Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro . DNA Research . 6 . 5 . 337–45 . Oct 1999 . 10574462 . 10.1093/dnares/6.5.337 . free .
• Perrot V, Vazquez-Prado J, Gutkind JS . Plexin B regulates Rho through the guanine nucleotide exchange factors leukemia-associated Rho GEF (LARG) and PDZ-RhoGEF . The Journal of Biological Chemistry . 277 . 45 . 43115–20 . Nov 2002 . 12183458 . 10.1074/jbc.M206005200 . free .
• Conrotto P, Corso S, Gamberini S, Comoglio PM, Giordano S . Interplay between scatter factor receptors and B plexins controls invasive growth . Oncogene . 23 . 30 . 5131–7 . Jul 2004 . 15184888 . 10.1038/sj.onc.1207650 . 24596233 .
• Artigiani S, Conrotto P, Fazzari P, Gilestro GF, Barberis D, Giordano S, Comoglio PM, Tamagnone L . Plexin-B3 is a functional receptor for semaphorin 5A . EMBO Reports . 5 . 7 . 710–4 . Jul 2004 . 15218527 . 1299100 . 10.1038/sj.embor.7400189 .
• Cheng J, Kapranov P, Drenkow J, Dike S, Brubaker S, Patel S, Long J, Stern D, Tammana H, Helt G, Sementchenko V, Piccolboni A, Bekiranov S, Bailey DK, Ganesh M, Ghosh S, Bell I, Gerhard DS, Gingeras TR . Transcriptional maps of 10 human chromosomes at 5-nucleotide resolution . Science . 308 . 5725 . 1149–54 . May 2005 . 15790807 . 10.1126/science.1108625 . 2005Sci...308.1149C . 13047538 .
• Hartwig C, Veske A, Krejcova S, Rosenberger G, Finckh U . Plexin B3 promotes neurite outgrowth, interacts homophilically, and interacts with Rin . BMC Neuroscience . 6 . 53 . 2006 . 16122393 . 1215486 . 10.1186/1471-2202-6-53 . free .
• Rujescu D, Meisenzahl EM, Krejcova S, Giegling I, Zetzsche T, Reiser M, Born CM, Möller HJ, Veske A, Gal A, Finckh U . Plexin B3 is genetically associated with verbal performance and white matter volume in human brain . Molecular Psychiatry . 12 . 2 . 190–4, 115 . Feb 2007 . 17033634 . 10.1038/sj.mp.4001903 . 2406935 .

Notes and References

1. Tamagnone L, Artigiani S, Chen H, He Z, Ming GI, Song H, Chedotal A, Winberg ML, Goodman CS, Poo M, Tessier-Lavigne M, Comoglio PM . Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates . Cell . 99 . 1 . 71–80 . Oct 1999 . 10520995 . 10.1016/S0092-8674(00)80063-X . free .
2. Web site: Entrez Gene: PLXNB3 plexin B3.
3. Perrot V, Vazquez-Prado J, Gutkind JS . Plexin B regulates Rho through the guanine nucleotide exchange factors leukemia-associated Rho GEF (LARG) and PDZ-RhoGEF . The Journal of Biological Chemistry . 277 . 45 . 43115–20 . Nov 2002 . 12183458 . 10.1074/jbc.M206005200 . free .
4. Swiercz JM, Kuner R, Behrens J, Offermanns S . Plexin-B1 directly interacts with PDZ-RhoGEF/LARG to regulate RhoA and growth cone morphology . Neuron . 35 . 1 . 51–63 . Jul 2002 . 12123608 . 10.1016/S0896-6273(02)00750-X . free .