PGPEP1 explained

The PGPEP1 gene in humans encodes the enzyme Pyroglutamyl-peptidase I.^[1]

Further reading

• Kimura K . Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes . Genome Res. . 16 . 1 . 55–65 . 2006 . 16344560 . 10.1101/gr.4039406 . 1356129 . vanc. Wakamatsu A . Suzuki Y . 3 . Ota . T . Nishikawa . T . Yamashita . R . Yamamoto . J . Sekine . M . Tsuritani . K .
• Valdivia A . Pyroglutamyl peptidase I and prolyl endopeptidase in human semen: increased activity in necrozoospermia . Regul. Pept. . 122 . 2 . 79–84 . 2005 . 15380924 . 10.1016/j.regpep.2004.05.005 . vanc. Irazusta J . Fernández D . 3 . Múgica . J . Ochoa . C . Casis . L . 24844740 .
• Minderman H, O'Loughlin KL, Pendyala L, Baer MR . VX-710 (biricodar) increases drug retention and enhances chemosensitivity in resistant cells overexpressing P-glycoprotein, multidrug resistance protein, and breast cancer resistance protein . Clin. Cancer Res. . 10 . 5 . 1826–34 . 2004 . 15014037 . 10.1158/1078-0432.CCR-0914-3 . free .
• Ota T . Complete sequencing and characterization of 21,243 full-length human cDNAs . Nat. Genet. . 36 . 1 . 40–5 . 2004 . 14702039 . 10.1038/ng1285 . vanc. Suzuki Y . Nishikawa T . 3 . Otsuki . Tetsuji . Sugiyama . Tomoyasu . Irie . Ryotaro . Wakamatsu . Ai . Hayashi . Koji . Sato . Hiroyuki . free .
• Dando PM . Pyroglutamyl-peptidase I: cloning, sequencing, and characterisation of the recombinant human enzyme . Protein Expr. Purif. . 28 . 1 . 111–9 . 2003 . 12651114 . 10.1016/S1046-5928(02)00632-0 . vanc. Fortunato M . Strand GB . 3 . Smith . TS . Barrett . AJ .
• Strausberg RL . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . vanc. Feingold EA . Grouse LH . 3 . Derge . JG . Klausner . RD . Collins . FS . Wagner . L . Shenmen . CM . Schuler . GD . 2002PNAS...9916899M . free .
• Gil J . Regional and subcellular distribution of soluble aminopeptidase in the human and the rat brain: a comparative study . Neuropeptides . 35 . 5–6 . 276–84 . 2002 . 12030812 . 10.1054/npep.2001.0870 . vanc. Larrinaga G . Meana JJ . 3 . Rodríguez-Puertas . R . Irazusta . J . Casis . L . 39976173 .
• Charli JL . Pyroglutamyl peptidase II inhibition specifically increases recovery of TRH released from rat brain slices . Neuropeptides . 14 . 3 . 191–6 . 1990 . 2575716 . 10.1016/0143-4179(89)90044-9 . vanc. Mendez M . Vargas MA . 3 . Cisneros . M. . Assai . M. . Joseph-Bravo . P. . Wilk . S. . 13735633 .

Notes and References

1. Web site: Entrez Gene: PGPEP1 pyroglutamyl-peptidase I.