POU3F1 explained

POU domain, class 3, transcription factor 1 (also known as Oct-6) is a protein that in humans is encoded by the POU3F1 gene.^{[1] [2]}

See also

• Octamer transcription factor

Further reading

• Monuki ES, Kuhn R, Weinmaster G, Trapp BD, Lemke G . Expression and activity of the POU transcription factor SCIP . Science . 249 . 4974 . 1300–3 . Sep 1990 . 1975954 . 10.1126/science.1975954 . 1990Sci...249.1300M .
• Suzuki N, Rohdewohld H, Neuman T, Gruss P, Schöler HR . Oct-6: a POU transcription factor expressed in embryonal stem cells and in the developing brain . The EMBO Journal . 9 . 11 . 3723–32 . Nov 1990 . 1976514 . 552128 . 10.1002/j.1460-2075.1990.tb07585.x.
• Zwilling S, König H, Wirth T . High mobility group protein 2 functionally interacts with the POU domains of octamer transcription factors . The EMBO Journal . 14 . 6 . 1198–208 . Mar 1995 . 7720710 . 398197 . 10.1002/j.1460-2075.1995.tb07103.x.
• Leger H, Sock E, Renner K, Grummt F, Wegner M . Functional interaction between the POU domain protein Tst-1/Oct-6 and the high-mobility-group protein HMG-I/Y . Molecular and Cellular Biology . 15 . 7 . 3738–47 . Jul 1995 . 7791781 . 230612 . 10.1128/mcb.15.7.3738.
• Faus I, Hsu HJ, Fuchs E . Oct-6: a regulator of keratinocyte gene expression in stratified squamous epithelia . Molecular and Cellular Biology . 14 . 5 . 3263–75 . May 1994 . 7909356 . 358693 . 10.1128/mcb.14.5.3263.
• Abdel-Rahman B, Fiddler M, Rappolee D, Pergament E . Expression of transcription regulating genes in human preimplantation embryos . Human Reproduction . 10 . 10 . 2787–92 . Oct 1995 . 8567814 . 10.1093/oxfordjournals.humrep.a135792 .
• Jaegle M, Mandemakers W, Broos L, Zwart R, Karis A, Visser P, Grosveld F, Meijer D . The POU factor Oct-6 and Schwann cell differentiation . Science . 273 . 5274 . 507–10 . Jul 1996 . 8662541 . 10.1126/science.273.5274.507 . 1996Sci...273..507J . 39349653 .
• Sock E, Enderich J, Rosenfeld MG, Wegner M . Identification of the nuclear localization signal of the POU domain protein Tst-1/Oct6 . The Journal of Biological Chemistry . 271 . 29 . 17512–8 . Jul 1996 . 8663425 . 10.1074/jbc.271.29.17512 . free .
• Malik KF, Jaffe H, Brady J, Young WS . The class III POU factor Brn-4 interacts with other class III POU factors and the heterogeneous nuclear ribonucleoprotein U . Brain Research. Molecular Brain Research . 45 . 1 . 99–107 . Apr 1997 . 9105675 . 10.1016/S0169-328X(96)00238-0 .
• Sumiyama K, Washio-Watanabe K, Ono T, Yoshida MC, Hayakawa T, Ueda S . Human class III POU genes, POU3F1 and POU3F3, map to chromosomes 1p34.1 and 3p14.2 . Mammalian Genome . 9 . 2 . 180–1 . Feb 1998 . 9457692 . 10.1007/s003359900721 . 9495282 .
• Arroyo EJ, Bermingham JR, Rosenfeld MG, Scherer SS . Promyelinating Schwann cells express Tst-1/SCIP/Oct-6 . The Journal of Neuroscience . 18 . 19 . 7891–902 . Oct 1998 . 9742157 . 10.1523/JNEUROSCI.18-19-07891.1998. 6792991 . free .
• Kawasaki T, Oka N, Tachibana H, Akiguchi I, Shibasaki H . Oct6, a transcription factor controlling myelination, is a marker for active nerve regeneration in peripheral neuropathies . Acta Neuropathologica . 105 . 3 . 203–8 . Mar 2003 . 12557005 . 10.1007/s00401-002-0630-9 . 2433/148771 . 2340303 . free .
• Beck IM, Müller M, Mentlein R, Sadowski T, Mueller MS, Paus R, Sedlacek R . Matrix metalloproteinase-19 expression in keratinocytes is repressed by transcription factors Tst-1 and Skn-1a: implications for keratinocyte differentiation . The Journal of Investigative Dermatology . 127 . 5 . 1107–14 . May 2007 . 17195013 . 10.1038/sj.jid.5700674 . free .
• Ryu EJ, Wang JY, Le N, Baloh RH, Gustin JA, Schmidt RE, Milbrandt J . Misexpression of Pou3f1 results in peripheral nerve hypomyelination and axonal loss . The Journal of Neuroscience . 27 . 43 . 11552–9 . Oct 2007 . 17959798 . 10.1523/JNEUROSCI.5497-06.2007 . 6673231 . free .

Notes and References

1. Tobler A, Schreiber E, Fontana A . The human Oct-6 POU transcription factor lacks the first 50 amino acids of its murine counterpart . Nucleic Acids Research . 21 . 4 . 1043 . Feb 1993 . 8451175 . 309249 . 10.1093/nar/21.4.1043 .
2. Web site: Entrez Gene: POU3F1 POU domain, class 3, transcription factor 1.