| Nikos Papanikou | |
| Fullname: | Nikolaos Papanikou |
| Birth Date: | 5 January 1992 |
| Birth Place: | Arta, Greece |
| Height: | 1.70 m |
| Currentclub: | Karaiskakis |
| Clubnumber: | 24 |
| Position: | Right-back |
| Years1: | 2011–2012 |
| Clubs1: | Tilikratis |
| Caps1: | 20 |
| Goals1: | 1 |
| Years2: | 2012–2013 |
| Clubs2: | Thrasyvoulos |
| Caps2: | 17 |
| Goals2: | 0 |
| Years3: | 2013– |
| Clubs3: | Karaiskakis |
| Caps3: | 90 |
| Goals3: | 2 |
| Pcupdate: | 17 March 2021 |
Nikos Papanikou (el|Νίκος Παπανίκου; born 5 January 1992) is a Greek professional footballer who plays as a right-back for Super League 2 club Karaiskakis.