Nicole de Savigny (1535–1590) was a French noblewoman. She was a mistress to Henry II of France in 1556–57.
De Savigny was the daughter of Georges II of Savigny and his first wife, Nicole d'Haussonville. She had a child with the king, Henry de Saint-Rémy (1557−1621). She was ancestress of Jeanne de Valois-Saint-Rémy.