| Position: | Running back |
| Number: | 35, 34 |
| Birth Date: | 17 December 1956 |
| Birth Place: | Alexander City, Alabama, U.S. |
| Height Ft: | 5 |
| Height In: | 9 |
| Weight Lb: | 210 |
| College: | Louisville |
| Draftyear: | 1979 |
| Draftround: | 10 |
| Draftpick: | 250 |
| Pastteams: |
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| Statlabel1: | Rushing yards |
| Statvalue1: | 423 |
| Statlabel2: | Rushing average |
| Statvalue2: | 3.4 |
| Statlabel3: | Touchdowns |
| Statvalue3: | 5 |
| Pfr: | PoolNa00 |
Nathan Lewis Poole (born December 17, 1956) is an American former professional football player who was a running back in the National Football League (NFL). He was selected in the 10th round (250th overall) of the 1979 NFL draft by the Cincinnati Bengals after playing college football for the University of Louisville. He played in the NFL for six seasons, two for the Bengals and four for the Denver Broncos.